Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | RXRA | P19793 | 2/20 | 0.45 |
| ▸ | RXRB | P28702 | 2/20 | 0.45 |
| ▸ | RXRG | P48443 | 2/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GRK6 | P43250 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10481172 | 0.86 | KDM4E (0.51) | KDM4EGRIN1GRIN2BRORCALDH1A1 | |
| SCHEMBL10481097 | 0.85 | KDM4E (0.49) | KDM4ERXRARXRBRXRGCTSK | |
| SCHEMBL8904639 | 0.83 | KDM4E (1.00) | KDM4ERXRARXRBRXRGFFAR1 | |
| SCHEMBL26679443 | 0.74 | APEX1 (0.47) | KDM4EFFAR1 | |
| SCHEMBL10481149 | 0.74 | GRIN1 (0.44) | KDM4EGRIN1GRIN2BRORCALDH1A1 | |
| SCHEMBL8337601 | 0.67 | SLC13A5 (0.67) | RXRARXRBRXRGCTSKMME | |
| SCHEMBL10775667 | 0.66 | KDM4E (0.68) | KDM4EALDH1A1 | |
| SCHEMBL23296145 | 0.65 | RXRA (0.58) | RXRARXRBRXRGS1PR5GRIN1 | |
| SCHEMBL10481117 | 0.64 | KDM4E (0.64) | KDM4EFFAR1ALDH1A1 | |
| SCHEMBL10481128 | 0.64 | KDM4E (0.60) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0099692-B1 | NEW FURANONE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-03-18 | — | — | EP | disclosed |
| EP-0189272-A2 | New furanone derivatives, processes for preparation thereof and use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-07-30 | — | — | EP | disclosed |
| US-4585789-A | ALDOSE REDUCTASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-04-29 | — | — | US | disclosed |
| EP-0099692-A1 | New furanone derivatives, process for the preparation thereof and use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-02-01 | — | — | EP | disclosed |