Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PDE5A | O76074 | 3/20 | 0.44 |
| ▸ | SCD | O00767 | 9/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CPT1A | P50416 | 1/20 | 0.41 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PDE1A | P54750 | 1/20 | 0.39 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2668009 | 0.89 | GRM5 (0.48) | MAPK1HTTLMNATSHRPDE5A | |
| SCHEMBL2667489 | 0.87 | GRM5 (0.50) | HTTKDM4ENPC1MAPTRAB9A | |
| SCHEMBL2667590 | 0.84 | MAPK1 (0.47) | MAPK1HTTLMNATSHRPDE5A | |
| SCHEMBL2667614 | 0.84 | ALDH1A1 (0.52) | MAPK1HTTPDE5ASCDALDH1A1 | |
| SCHEMBL2667629 | 0.84 | ALDH1A1 (0.52) | MAPK1HTTPDE5ASCDALDH1A1 | |
| SCHEMBL2667668 | 0.84 | ALDH1A1 (0.52) | MAPK1HTTPDE5ASCDALDH1A1 | |
| SCHEMBL2667648 | 0.81 | GRM5 (0.46) | MAPK1HTTLMNATSHRPDE5A | |
| SCHEMBL2667587 | 0.81 | SCD (0.51) | MAPK1HTTPDE5ASCDALDH1A1 | |
| SCHEMBL2667704 | 0.81 | SCD (0.51) | MAPK1HTTPDE5ASCDALDH1A1 | |
| SCHEMBL9071000 | 0.80 | KDM4E (0.50) | MAPK1HTTLMNAPDE5ASCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |