Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 19/20 | 0.45 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667808 | 0.92 | GCK (0.47) | GCKRARGRARARARB | |
| SCHEMBL9071023 | 0.91 | GCK (0.54) | GCKRARGSMN1; SMN2RARARARB | |
| SCHEMBL2667583 | 0.89 | GCK (0.49) | GCKRARG | |
| SCHEMBL9070927 | 0.89 | SMN1; SMN2 (0.42) | GCKSMN1; SMN2 | |
| SCHEMBL2667571 | 0.84 | GCK (0.47) | GCKKCNH2 | |
| SCHEMBL2668001 | 0.84 | GCK (0.66) | GCKRARGRARARARB | |
| SCHEMBL9071056 | 0.84 | GCK (0.59) | GCKKCNH2 | |
| SCHEMBL2667830 | 0.83 | GCK (0.57) | GCKRARGRARARARB | |
| SCHEMBL2667553 | 0.82 | GCK (0.47) | GCKKCNH2 | |
| SCHEMBL9071059 | 0.82 | GCK (0.51) | GCKRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |