Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 19/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667377 | 0.90 | ALDH1A1 (0.44) | GCKALDH1A1TSHR | |
| SCHEMBL9071023 | 0.88 | GCK (0.54) | GCKKCNH2 | |
| SCHEMBL2667583 | 0.86 | GCK (0.49) | GCK | |
| SCHEMBL2667553 | 0.85 | GCK (0.47) | GCKKCNH2ALDH1A1 | |
| SCHEMBL9070940 | 0.85 | GCK (0.67) | GCK | |
| SCHEMBL2668005 | 0.84 | GCK (0.45) | GCKKCNH2 | |
| SCHEMBL2667808 | 0.84 | GCK (0.47) | GCK | |
| SCHEMBL9071008 | 0.84 | GCK (0.45) | GCKALDH1A1TSHR | |
| SCHEMBL9070939 | 0.83 | GCK (0.53) | GCK | |
| SCHEMBL2667565 | 0.82 | GCK (0.65) | GCKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |