Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 8/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953102 | 0.79 | BACE1 (0.63) | BACE1EGFRMAPTNPSR1RXFP1 | |
| SCHEMBL1014901 | 0.79 | BACE1 (0.63) | BACE1EGFRMAPTNPSR1RXFP1 | |
| SCHEMBL10831447 | 0.77 | BACE1 (0.61) | BACE1EGFRMAPTNPSR1RXFP1 | |
| SCHEMBL6562672 | 0.77 | BACE1 (0.61) | BACE1EGFRMAPTNPSR1NPC1 | |
| SCHEMBL14564095 | 0.75 | EGFR (0.65) | BACE1EGFRMAPTNPSR1NPC1 | |
| SCHEMBL24455990 | 0.73 | BACE1 (0.56) | BACE1EGFRMAPTNPSR1NPC1 | |
| SCHEMBL17300476 | 0.73 | BACE1 (0.56) | BACE1EGFRMAPTNPSR1NPC1 | |
| SCHEMBL29652995 | 0.73 | BACE1 (0.56) | BACE1EGFRMAPTNPSR1NPC1 | |
| SCHEMBL1648673 | 0.72 | BACE1 (1.00) | BACE1EGFRNPSR1RXFP1 | |
| SCHEMBL1648672 | 0.72 | BACE1 (1.00) | BACE1EGFRNPSR1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075847-A2 | GLUCOKINASE ACTIVATORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-07-05 | — | — | WO | disclosed |