Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 8/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28267268 | 0.79 | MEN1 (0.57) | KDM4EPOLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14420964 | 0.78 | MEN1 (0.67) | MEN1KMT2ASMN1; SMN2MAPTHTT | |
| SCHEMBL2658687 | 0.77 | ALDH1A1 (0.64) | FFAR2KDM4EPOLBCYP1A2CYP2D6 | |
| SCHEMBL1464767 | 0.76 | MAPT (0.57) | FFAR2CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL14417062 | 0.74 | MEN1 (0.55) | FFAR2MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL592704 | 0.74 | MEN1 (0.65) | MEN1KMT2ASMN1; SMN2MAPTHTT | |
| SCHEMBL2655802 | 0.73 | NPC1 (0.49) | FFAR2KDM4EPOLBCYP1A2CYP2D6 | |
| SCHEMBL2901112 | 0.73 | NR3C1 (0.86) | — | |
| SCHEMBL2656574 | 0.73 | MEN1 (0.63) | MEN1KMT2ASMN1; SMN2MAPTHTT | |
| SCHEMBL14532379 | 0.72 | POLB (0.51) | FFAR2KDM4EPOLBCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008104994-A2 | 2,2,2-TRI-SUBSTITUTED ACETAMIDE DERIVATIVES AS GLUCOKINASE ACTIVATORS, THEIR PROCESS AND PHARMACEUTICAL APPLICATION | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2008-09-04 | — | — | WO | disclosed |