Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
| ▸ | GABRE | P78334 | 1/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL713174 | 0.91 | MAOA (0.41) | PDGFRBPDGFRAMCL1MAOAMAOB | |
| SCHEMBL13639547 | 0.88 | PDGFRB (0.39) | PDGFRBPDGFRAMCL1CYP3A4MAOA | |
| SCHEMBL10206516 | 0.88 | MCL1 (0.41) | PDGFRBPDGFRAMCL1CYP3A4MAOA | |
| SCHEMBL711734 | 0.87 | GCK (0.39) | PDGFRBPDGFRAMCL1CYP3A4MAOA | |
| SCHEMBL711045 | 0.86 | EDNRA (0.39) | PDGFRBPDGFRAMCL1CYP3A4MAOA | |
| SCHEMBL711526 | 0.85 | BCHE (0.41) | PDGFRBPDGFRAMAOAMAOBEDNRA | |
| SCHEMBL710310 | 0.84 | GCK (0.47) | MCL1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL710136 | 0.84 | MAPT (0.43) | PDGFRBPDGFRAMCL1CYP3A4MAOB | |
| SCHEMBL711592 | 0.84 | MCL1 (0.40) | PDGFRBPDGFRAMCL1PTPN1ALOX5 | |
| SCHEMBL713544 | 0.84 | FFAR1 (0.40) | PDGFRBPDGFRAMCL1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007028135-A2 | IMIDAZOPYRIDINE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-03-08 | — | — | WO | disclosed |