Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 14/20 | 0.69 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.65 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | PKM | P14618 | 2/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.63 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.63 |
| ▸ | RELA | Q04206 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9374304 | 0.89 | MRGPRX4 (0.74) | MRGPRX4TP53PKMNFKB1NFKB2 | |
| SCHEMBL9372934 | 0.87 | MAOB (0.53) | MRGPRX4NR4A2TP53PKMNFKB1 | |
| SCHEMBL9372701 | 0.87 | MRGPRX4 (0.69) | MRGPRX4TP53PKMNFKB1NFKB2 | |
| SCHEMBL4406160 | 0.85 | NR4A2 (0.87) | MRGPRX4NR4A2TP53PKMNFKB1 | |
| SCHEMBL765921 | 0.85 | FOLH1 (0.61) | MRGPRX4 | |
| SCHEMBL27655015 | 0.83 | NR4A2 (0.72) | MRGPRX4NR4A2TP53PKMNFKB1 | |
| SCHEMBL1122713 | 0.83 | NR4A2 (0.94) | MRGPRX4NR4A2SMN1; SMN2 | |
| SCHEMBL10661819 | 0.83 | MRGPRX4 (0.68) | MRGPRX4NR4A2TP53PKMNFKB1 | |
| SCHEMBL4138759 | 0.82 | NR4A2 (0.81) | MRGPRX4NR4A2TP53PKMNFKB1 | |
| SCHEMBL321092 | 0.82 | MAOB (0.62) | NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600084-A1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |
| WO-1993003012-A1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-18 | — | — | WO | disclosed |