Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 19/20 | 0.57 |
| ▸ | BAK1 | Q16611 | 4/20 | 0.57 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 15/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26681233 | 0.91 | BCL2 (0.47) | BCL2BAK1BCL2L1 | |
| SCHEMBL26680907 | 0.91 | BCL2 (0.70) | BCL2BAK1CHEK1BCL2L1 | |
| SCHEMBL26682948 | 0.89 | BCL2 (0.60) | BCL2BAK1CHEK1BCL2L1 | |
| SCHEMBL26682508 | 0.86 | BCL2 (0.46) | BCL2BAK1BCL2L1 | |
| SCHEMBL26680848 | 0.86 | DGAT2 (0.44) | BCL2BAK1 | |
| SCHEMBL26682227 | 0.86 | CHEK1 (0.47) | CHEK1 | |
| SCHEMBL26680600 | 0.84 | BCL2 (0.54) | BCL2BAK1CHEK1BCL2L1 | |
| SCHEMBL30687634 | 0.84 | BCL2 (0.40) | BCL2BAK1BCL2L1 | |
| SCHEMBL26682139 | 0.84 | BCL2 (0.40) | BCL2BAK1BCL2L1 | |
| SCHEMBL26682702 | 0.84 | CHEK1 (0.49) | BCL2BAK1CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4279476-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-11-22 | — | — | EP | disclosed |