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SCHEMBL26683259

SCHEMBL26683259

COC(=O)C1=C(c2ccccc2)C[C@@H]2CC[C@H]1N2

nearest known ligand 0.60

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ SLC6A3 Q01959 19/20 0.60
▸ SLC6A4 P31645 8/20 0.52
▸ SLC6A2 P23975 1/20 0.42
▸ CHRM2 P08172 1/20 0.40
▸ CHRM4 P08173 1/20 0.40
▸ CHRM5 P08912 1/20 0.40
▸ CHRM1 P11229 1/20 0.40
▸ CHRM3 P20309 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26683256 1.00 SLC6A3 (0.60) SLC6A3SLC6A4SLC6A2CHRM2CHRM4
SCHEMBL6521453 0.86 SLC6A3 (0.56) SLC6A3SLC6A4
SCHEMBL7321371 0.85 SLC6A3 (0.67) SLC6A3SLC6A4SLC6A2
SCHEMBL3418076 0.85 SLC6A3 (0.67) SLC6A3SLC6A4SLC6A2
SCHEMBL6515132 0.81 SLC6A3 (0.66) SLC6A3SLC6A4SLC6A2
SCHEMBL6762602 0.70 SLC6A3 (1.00) SLC6A3SLC6A4SLC6A2
SCHEMBL6767667 0.69 SLC6A3 (0.76) SLC6A3SLC6A4
SCHEMBL26683852 0.69 SLC6A3 (1.00) SLC6A3SLC6A4
SCHEMBL4138870 0.68 SLC6A3 (0.39) SLC6A3SLC6A4SLC6A2
SCHEMBL4147504 0.68 SLC6A3 (0.39) SLC6A3SLC6A4SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023219199-A1 MANUFACTURING METHOD FOR FP-CIT PRECURSOR, AND MANUFACTURING METHOD FOR [18F]FP-CIT USING FP-CIT PRECURSOR MANUFACTURED THEREBY (주)듀켐바이오 2023-11-16 — — WO disclosed