Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.39 |
| ▸ | REN | P00797 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4147504 | 1.00 | SLC6A3 (0.39) | SLC6A3SLC6A4RENSLC6A2CHRNB2 | |
| SCHEMBL4138873 | 1.00 | SLC6A3 (0.39) | SLC6A3SLC6A4RENSLC6A2CHRNB2 | |
| SCHEMBL3421449 | 0.87 | SLC6A3 (0.39) | SLC6A3SLC6A4RENCHRNA7CYP3A4 | |
| SCHEMBL4135078 | 0.87 | SLC6A3 (0.39) | SLC6A3SLC6A4RENCHRNA7CYP3A4 | |
| SCHEMBL4142238 | 0.81 | SLC6A3 (0.47) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL4142236 | 0.81 | SLC6A3 (0.47) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL4149439 | 0.81 | SLC6A3 (0.47) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL4140195 | 0.80 | SLC6A3 (0.48) | SLC6A3SLC6A4SLC6A2ALDH1A1 | |
| SCHEMBL4140196 | 0.80 | SLC6A3 (0.48) | SLC6A3SLC6A4SLC6A2ALDH1A1 | |
| SCHEMBL4140231 | 0.80 | SLC6A3 (0.48) | SLC6A3SLC6A4SLC6A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090208415-A1 | Tropane compounds | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2009-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090208415-A1 | Tropane compounds | TPM3, TPM4, ADRA2C | SLC6A3 196/4885SLC6A4 217/4885REN 3013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.