SCHEMBL26684089

SCHEMBL26684089

CN1CCN(c2noc3cc(N4CCC(=O)NC4=O)ccc23)CC1

nearest known ligand 0.42

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 7/20 0.42
▸ CRBN Q96SW2 7/20 0.42
▸ HTR2A P28223 10/20 0.38
▸ HTR1A P08908 7/20 0.38
▸ DRD2 P14416 6/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30688293 1.00 DDB1 (0.42) DDB1CRBNHTR2AHTR1ADRD2
SCHEMBL30688301 0.88 CRBN (0.43) DDB1CRBNHTR2AHTR1ADRD2
SCHEMBL26683625 0.88 CRBN (0.43) DDB1CRBNHTR2AHTR1ADRD2
SCHEMBL26683716 0.87 DDB1 (0.39) DDB1CRBNHTR2ADRD2
SCHEMBL30688294 0.87 DDB1 (0.39) DDB1CRBNHTR2ADRD2
Hydrochloric Acid SCHEMBL25337439 0.87 CRBN (0.42) DDB1CRBNHTR2AHTR1ADRD2
Hydrochloric Acid SCHEMBL29507035 0.87 CRBN (0.42) DDB1CRBNHTR2AHTR1ADRD2
SCHEMBL29507006 0.86 DDB1 (0.40) DDB1CRBNHTR2AHTR1ADRD2
SCHEMBL26684220 0.86 DDB1 (0.40) DDB1CRBNHTR2AHTR1ADRD2
SCHEMBL30688281 0.82 DDB1 (0.43) DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230374007-A1 COMPOUNDS AND THEIR USE IN TREATING CANCER ASTRAZENECA AB (SE) 2023-11-23 — — US disclosed
US-20230374007-A1 COMPOUNDS AND THEIR USE IN TREATING CANCER ASTRAZENECA AB (SE) 2023-11-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230374007-A1 COMPOUNDS AND THEIR USE IN TREATING CANCER RARA, RARG, RARB DDB1 4162/4885CRBN 2312/4885HTR2A 4101/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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