Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 7/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 7/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | SMO | Q99835 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RPLP1 | P05386 | 1/20 | 0.34 |
| ▸ | RPLP0 | P05388 | 1/20 | 0.34 |
| ▸ | RPS17 | P08708 | 1/20 | 0.34 |
| ▸ | RPSA | P08865 | 1/20 | 0.34 |
| ▸ | RPS2 | P15880 | 1/20 | 0.34 |
| ▸ | RPL35A | P18077 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26683716 | 1.00 | DDB1 (0.39) | DDB1CRBNCASP6GFERSMO | |
| SCHEMBL26684220 | 0.91 | DDB1 (0.40) | DDB1CRBNDRD2HTR2AHTR7 | |
| SCHEMBL29507006 | 0.91 | DDB1 (0.40) | DDB1CRBNDRD2HTR2AHTR7 | |
| SCHEMBL30688293 | 0.87 | DDB1 (0.42) | DDB1CRBNDRD2HTR2A | |
| SCHEMBL26684089 | 0.87 | DDB1 (0.42) | DDB1CRBNDRD2HTR2A | |
| SCHEMBL26848888 | 0.87 | DDB1 (0.43) | DDB1CRBNALDH1A1 | |
| SCHEMBL30688281 | 0.87 | DDB1 (0.43) | DDB1CRBNALDH1A1 | |
| SCHEMBL30688301 | 0.84 | CRBN (0.43) | DDB1CRBNDRD2HTR2A | |
| SCHEMBL26683625 | 0.84 | CRBN (0.43) | DDB1CRBNDRD2HTR2A | |
| Hydrochloric Acid SCHEMBL25337439 | 0.83 | CRBN (0.42) | DDB1CRBNDRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230374007-A1 | COMPOUNDS AND THEIR USE IN TREATING CANCER | ASTRAZENECA AB (SE) | 2023-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230374007-A1 | COMPOUNDS AND THEIR USE IN TREATING CANCER | RARA, RARG, RARB | DDB1 4162/4885CRBN 2312/4885CASP6 461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.