Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2668649 | 0.84 | AAK1 (0.45) | ALDH1A1ALOX5KMT2APARP10 | |
| SCHEMBL2668512 | 0.82 | NPC1 (0.47) | ALDH1A1ALOX5PDK1OPRL1 | |
| SCHEMBL2668586 | 0.81 | ALOX5 (0.47) | ALOX5PARP10EPHX2 | |
| SCHEMBL2668498 | 0.81 | PARP10 (0.44) | ALDH1A1PARP10EPHX2 | |
| SCHEMBL2668509 | 0.80 | MEN1 (0.41) | ALDH1A1ALOX5KMT2APSEN1PSEN2 | |
| SCHEMBL12204358 | 0.79 | ALOX5 (0.40) | ALOX5PARP10PDK1OPRL1 | |
| SCHEMBL2668513 | 0.77 | ALOX5 (0.42) | ALOX5PARP10PDK1 | |
| SCHEMBL2668511 | 0.76 | NPC1 (0.41) | L3MBTL1ALOX5KMT2APSEN1PSEN2 | |
| SCHEMBL2668587 | 0.75 | ALOX5 (0.41) | ALOX5KMT2APARP10 | |
| SCHEMBL2668497 | 0.74 | SLC6A2 (0.44) | ALOX5EPHX2OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008084043-A1 | UREA GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2008-07-17 | — | — | WO | disclosed |