Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12204358 | 0.85 | ALOX5 (0.40) | ALOX5EPHX1TRPA1PARP10ADORA2A | |
| SCHEMBL12204197 | 0.85 | ALOX5 (0.40) | ALOX5MEN1KMT2ALPAR1LPAR5 | |
| SCHEMBL2668586 | 0.77 | ALOX5 (0.47) | ALOX5PARP10 | |
| SCHEMBL2668428 | 0.75 | ALDH1A1 (0.41) | ALOX5KMT2APARP10 | |
| SCHEMBL2668649 | 0.75 | AAK1 (0.45) | ALOX5MEN1KMT2APARP10 | |
| SCHEMBL2668498 | 0.74 | PARP10 (0.44) | PARP10 | |
| SCHEMBL2668459 | 0.74 | KMT2A (0.43) | ALOX5MEN1KMT2A | |
| SCHEMBL2668510 | 0.74 | NPSR1 (0.44) | ALOX5KMT2A | |
| SCHEMBL2668509 | 0.74 | MEN1 (0.41) | ALOX5EPHX1MEN1KMT2A | |
| SCHEMBL2668670 | 0.74 | ALOX5 (0.36) | ALOX5MEN1KMT2ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007006814-A1 | UREA GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2007-01-18 | — | — | WO | disclosed |