Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.33 |
| ▸ | VHL | P40337 | 2/20 | 0.30 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.30 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.30 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30632478 | 1.00 | PBRM1 (0.33) | PBRM1VHLNPY5RSMARCA2SMARCA4 | |
| SCHEMBL30632521 | 0.93 | MAPT (0.34) | PBRM1VHLNPY5RSMARCA2SMARCA4 | |
| SCHEMBL26684930 | 0.93 | MAPT (0.34) | PBRM1VHLNPY5RSMARCA2SMARCA4 | |
| SCHEMBL30632497 | 0.87 | — | — | |
| SCHEMBL26684810 | 0.87 | — | — | |
| SCHEMBL30632490 | 0.81 | TACR3 (0.32) | NPY5RMAPT | |
| SCHEMBL26685067 | 0.81 | TACR3 (0.32) | NPY5RMAPT | |
| SCHEMBL26683396 | 0.80 | NPC1 (0.30) | — | |
| SCHEMBL30666222 | 0.80 | NPC1 (0.30) | — | |
| SCHEMBL30632489 | 0.77 | VHL (0.58) | PBRM1VHLSMARCA2SMARCA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220129-A1 | BENZOYPARAZINE PYRAZINES ANE THEIR USES | FOGHORN THERAPEUTICS INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023220129-A1 | BENZOYPARAZINE PYRAZINES ANE THEIR USES | FOGHORN THERAPEUTICS INC. (US) | 2023-11-16 | — | — | WO | disclosed |