⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26684810 | 1.00 | — | — | |
| SCHEMBL26685067 | 0.92 | TACR3 (0.32) | — | |
| SCHEMBL30632490 | 0.92 | TACR3 (0.32) | — | |
| SCHEMBL30632478 | 0.87 | PBRM1 (0.33) | — | |
| SCHEMBL26685136 | 0.87 | PBRM1 (0.33) | — | |
| SCHEMBL26683396 | 0.86 | NPC1 (0.30) | — | |
| SCHEMBL30666222 | 0.86 | NPC1 (0.30) | — | |
| SCHEMBL30632521 | 0.80 | MAPT (0.34) | — | |
| SCHEMBL26684930 | 0.80 | MAPT (0.34) | — | |
| SCHEMBL30632579 | 0.79 | SMARCA2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119998278-A | Compounds and uses thereof | 福宏治疗公司 | 2025-05-13 | — | — | CN | disclosed |
| EP-4522278-A1 | BENZOYPARAZINE PYRAZINES ANE THEIR USES | Foghorn Therapeutics Inc. (US) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023220129-A1 | BENZOYPARAZINE PYRAZINES ANE THEIR USES | FOGHORN THERAPEUTICS INC. (US) | 2023-11-16 | — | — | WO | disclosed |