SCHEMBL266852

SCHEMBL266852

Fc1cc(Br)ccc1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29453084 1.00
SCHEMBL1508806 0.97 LMNA (0.44)
Fluoride SCHEMBL28088569 0.97 LMNA (0.44)
SCHEMBL2822580 0.97 LMNA (0.44)
SCHEMBL8016889 0.84 ALOX5AP (0.51)
SCHEMBL8092321 0.83 AHR (0.44)
SCHEMBL30291914 0.79
SCHEMBL330695 0.79
Magnesium SCHEMBL30216620 0.77 IDO1 (0.43)
SCHEMBL5343969 0.77 IDO1 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 820 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116426295-A Preparation method of side fluorine-containing terphenyl liquid crystal monomer 河北凡克新材料有限公司 2023-07-14 CN claimed
CN-106659721-B Process for the preparation of a medicament 基因泰克公司 2021-01-01 CN claimed
US-20200190061-A1 PROCESS FOR THE MANUFACTURING OF MEDICAMENTS GENENTECH, INC. (US) 2020-06-18 US claimed
CN-111253210-A Preparation method of 4 '-alkyl-2, 4,3' -trifluoro-terphenyl liquid crystal monomer 中节能万润股份有限公司 2020-06-09 CN claimed
US-10611753-B2 Process for the manufacturing of medicaments GENENTECH, INC. (US) 2020-04-07 US claimed
EP-3129025-B1 PROCESS FOR THE MANUFACTURING OF MEDICAMENTS GENENTECH INC (US) 2019-05-15 EP claimed
US-20180134685-A1 PROCESS FOR THE MANUFACTURING OF MEDICAMENTS GENENTECH, INC. (US) 2018-05-17 US claimed
US-20170022183-A1 PROCESS FOR THE MANUFACTURING OF MEDICAMENTS GENENTECH, INC. (US) 2017-01-26 US claimed
US-20260150574-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DIODE, ORGANIC OPTOELECTRONIC DIODE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2026-05-28 US disclosed
EP-4743085-A2 COMPOUNDS, COMPOSITIONS, AND METHODS Tenvie Therapeutics, Inc. (US) 2026-05-20 EP disclosed
CN-116829545-B Substituted pyrazolylpiperidine carboxylic acids 拜耳公司 2026-05-15 CN disclosed
US-20260124309-A1 STAT6 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2026-05-07 US disclosed
WO-2026090477-A1 HELICASE INHIBITORS AND USES THEREOF KIMIA THERAPEUTICS, INC. (US) 2026-04-30 WO disclosed
US-20260123274-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2026-04-30 US disclosed
WO-1991002043-A1 FLUORO-CHLORO-BENZENE DERIVATIVES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1991-02-21 WO disclosed
WO-1990015113-A1 FLUORO-CHLORO-BENZENE DERIVATIVES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1990-12-13 WO disclosed
EP-0109606-B1 PROCESS FOR THE FORMYLATION OF ARYL HALIDES BAYER AG (DE) 1986-01-22 EP disclosed
US-4536344-A USING A PHOSPINE OR PHOSPHITE BAYER AKTIENGESELLSCHAFT (DE) 1985-08-20 US disclosed
EP-0109606-A1 Process for the formylation of aryl halides BAYER AG (DE) 1984-05-30 EP disclosed
US-4238611-A Polysubstituted derivatives of 10-piperazinodibenzo (b,f) thiepine SPOFA, UNITED PHARMACEUTICAL WORKS (CS) 1980-12-09 US disclosed