Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL330695 | 0.97 | — | — | |
| SCHEMBL30291914 | 0.97 | — | — | |
| SCHEMBL5343969 | 0.95 | IDO1 (0.43) | IDO1MAPTKMT2AALDH1A1MEN1 | |
| Fluorobenzene SCHEMBL27550190 | 0.85 | NPC1 (0.40) | IDO1MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL29453084 | 0.77 | — | — | |
| SCHEMBL266852 | 0.77 | — | — | |
| Fluoride SCHEMBL28088569 | 0.75 | LMNA (0.44) | MAPTKMT2AALDH1A1MEN1HTT | |
| SCHEMBL1508806 | 0.75 | LMNA (0.44) | MAPTKMT2AALDH1A1MEN1HTT | |
| SCHEMBL2822580 | 0.75 | LMNA (0.44) | IDO1MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL26601050 | 0.74 | SOS1 (0.58) | MAPTSLC6A4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115697327-A | 5-oxo-pyrrolidine-3-carboxamides as NAV1.8 inhibitors | 默沙东有限责任公司 | 2023-02-03 | — | — | CN | disclosed |