Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1F | P30939 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.35 |
| ▸ | PRKDC | P78527 | 2/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | MTOR | P42345 | 2/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30632780 | 1.00 | OPRK1 (0.39) | OPRK1HTR1AHTR1DHTR1FHRH3 | |
| SCHEMBL26685834 | 0.94 | TYRO3 (0.41) | OPRK1HTR1AHTR1DHTR1FTYRO3 | |
| SCHEMBL30632696 | 0.94 | TYRO3 (0.41) | OPRK1HTR1AHTR1DHTR1FTYRO3 | |
| SCHEMBL26685782 | 0.93 | HTR1A (0.43) | OPRK1HTR1AHTR1DHTR1FHRH3 | |
| SCHEMBL30632621 | 0.93 | HTR1A (0.43) | OPRK1HTR1AHTR1DHTR1FHRH3 | |
| SCHEMBL26685570 | 0.91 | OPRK1 (0.41) | OPRK1HTR1AHTR1DHTR1FTYRO3 | |
| SCHEMBL30632693 | 0.91 | OPRK1 (0.41) | OPRK1HTR1AHTR1DHTR1FTYRO3 | |
| SCHEMBL30632637 | 0.89 | MAPK1 (0.37) | OPRK1HTR1AHTR1DHTR1FTYRO3 | |
| SCHEMBL26685697 | 0.89 | MAPK1 (0.37) | OPRK1HTR1AHTR1DHTR1FTYRO3 | |
| SCHEMBL30632705 | 0.87 | MAPK1 (0.39) | OPRK1HTR1AHTR1DHTR1FHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220046-A1 | TYK2 INHIBITORS | BIOGEN MA INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023220046-A1 | TYK2 INHIBITORS | BIOGEN MA INC. (US) | 2023-11-16 | — | — | WO | disclosed |