SCHEMBL26686149

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL31420489	0.91	ULK1 (0.41)	CDC7DYRK1ACLK2CLK3JAK2
	SCHEMBL26686049	0.91	ULK1 (0.41)	CDC7DYRK1ACLK2CLK3JAK2
	SCHEMBL26686128	0.90	CCNK (0.41)	CDC7DYRK1ACLK2CLK3JAK2
	SCHEMBL26685993	0.90	GSK3B (0.44)	CDC7DYRK1ACLK2CLK3JAK2
	SCHEMBL26686078	0.86	DYRK1A (0.40)	CDC7DYRK1ACLK2CLK3JAK2
	SCHEMBL26686020	0.84	GSK3B (0.49)	CDC7DYRK1ACLK2JAK2TYK2
	SCHEMBL31240566	0.83	NUDT1 (0.39)	CDC7DYRK1ACLK2JAK2KDM5B
	SCHEMBL26686645	0.83	NUDT1 (0.39)	CDC7DYRK1ACLK2JAK2KDM5B
	SCHEMBL26685943	0.82	MAPK14 (0.50)	CDC7DYRK1ACLK2CLK3JAK2
	SCHEMBL26685743	0.82	JAK2 (0.46)	DYRK1ACLK2CLK3JAK2CCNK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.