SCHEMBL26686172

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL26686058	0.94	JAK2 (0.53)	JAK2CCNKCDK12WNT1DYRK1A
	SCHEMBL26686672	0.91	DYRK1A (0.42)	JAK2CCNKCDK12WNT1DYRK1A
	SCHEMBL26686381	0.89	JAK2 (0.60)	JAK2CCNKCDK12WNT1DYRK1A
	SCHEMBL26685962	0.85	DYRK1A (0.43)	JAK2CCNKCDK12WNT1DYRK1A
	SCHEMBL31240548	0.85	TBK1 (0.46)	JAK2WNT1DYRK1AMAPK8CAMKK2
	SCHEMBL26685942	0.80	CCNK (0.55)	JAK2CCNKCDK12DYRK1AAURKA
	SCHEMBL31240247	0.80	JAK2 (0.67)	JAK2AURKAAURKBMAPK8CAMKK2
	SCHEMBL31240333	0.79	JAK2 (0.46)	JAK2WNT1DYRK1AMAPK8CAMKK2
	SCHEMBL26685993	0.79	GSK3B (0.44)	JAK2DYRK1AGSK3BKCNH2TBK1
	SCHEMBL26686734	0.79	CCNK (0.44)	JAK2CCNKCDK12AURKAAURKB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.