Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | TBK1 | Q9UHD2 | 7/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.44 |
| ▸ | WNT1 | P04628 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 6/20 | 0.43 |
| ▸ | CAMKK2 | Q96RR4 | 6/20 | 0.43 |
| ▸ | CHUK | O15111 | 5/20 | 0.43 |
| ▸ | INSR | P06213 | 4/20 | 0.43 |
| ▸ | CDK9 | P50750 | 2/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.42 |
| ▸ | CLK3 | P49761 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240589 | 0.84 | TBK1 (0.60) | TBK1DYRK1ACLK2CLK3 | |
| SCHEMBL31240247 | 0.83 | JAK2 (0.67) | JAK2TBK1MAPK8CAMKK2CHUK | |
| SCHEMBL26686058 | 0.81 | JAK2 (0.53) | JAK2TBK1DYRK1AWNT1MAPK8 | |
| SCHEMBL31240352 | 0.81 | TBK1 (0.61) | JAK2TBK1DYRK1AMAPK8CAMKK2 | |
| SCHEMBL31240694 | 0.81 | CDK9 (0.49) | CDK9CCNT1CDK1CDK2CASP3 | |
| SCHEMBL31240546 | 0.81 | CAMKK2 (0.54) | JAK2TBK1DYRK1AWNT1MAPK8 | |
| SCHEMBL31240548 | 0.81 | TBK1 (0.46) | JAK2TBK1DYRK1AWNT1MAPK8 | |
| SCHEMBL26685929 | 0.80 | JAK2 (0.61) | JAK2DYRK1AWNT1 | |
| SCHEMBL31240622 | 0.80 | DYRK1A (0.48) | JAK2DYRK1AMAPK8CHUKCDK9 | |
| SCHEMBL26686172 | 0.79 | JAK2 (0.51) | JAK2TBK1DYRK1AWNT1MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | claimed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | claimed |