Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.55 |
| ▸ | SLC22A12 | Q96S37 | 17/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.43 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2668679 | 0.90 | SLC40A1 (0.54) | SLC40A1SLC22A12MEN1ALDH1A1KMT2A | |
| SCHEMBL2668794 | 0.81 | MEN1 (0.61) | SLC40A1SLC22A12MEN1ALDH1A1KMT2A | |
| SCHEMBL2668598 | 0.79 | SLC40A1 (0.55) | SLC40A1SLC22A12MEN1ALDH1A1KMT2A | |
| SCHEMBL29956573 | 0.78 | CYP2A6 (0.47) | MEN1ALDH1A1KMT2A | |
| SCHEMBL13675180 | 0.75 | CYP2C9 (0.54) | SLC40A1MEN1ALDH1A1KMT2ACYP2C9 | |
| SCHEMBL2660427 | 0.75 | HIF1A (0.51) | SLC40A1SLC22A12MEN1ALDH1A1KMT2A | |
| SCHEMBL1653280 | 0.74 | NFKBIA (0.51) | ALDH1A1 | |
| SCHEMBL16235103 | 0.71 | SLC22A12 (0.63) | SLC40A1SLC22A12MEN1ALDH1A1KMT2A | |
| SCHEMBL11973658 | 0.71 | SLC40A1 (1.00) | SLC40A1SLC22A12MEN1KMT2A | |
| SCHEMBL30925425 | 0.71 | SLC40A1 (1.00) | SLC40A1SLC22A12MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2508524-A2 | Indole compound | Takeda Pharmaceutical Company Limited (JP) | 2012-10-10 | — | — | EP | disclosed |
| WO-2008050821-A1 | INDOLE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-02 | — | — | WO | disclosed |