Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CKS1B | P61024 | 1/20 | 0.50 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.50 |
| ▸ | TUBB | P07437 | 1/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1654047 | 0.79 | TUBB4A (0.52) | CYP2C9CYP2C19LMNAALDH1A1KMT2A | |
| SCHEMBL1654857 | 0.78 | TUBB4A (0.48) | CYP2C9CYP2C19LMNAALDH1A1KMT2A | |
| SCHEMBL2668598 | 0.77 | SLC40A1 (0.55) | ALDH1A1KMT2AMAPTSLC40A1TUBB4A | |
| SCHEMBL1653280 | 0.77 | NFKBIA (0.51) | LMNAALDH1A1TDP1OPRK1HTT | |
| SCHEMBL2367682 | 0.75 | NR3C1 (0.64) | CYP2C9CYP2C19LMNAALDH1A1KMT2A | |
| SCHEMBL2668792 | 0.75 | SLC40A1 (0.55) | CYP2C9ALDH1A1KMT2ASLC40A1MEN1 | |
| SCHEMBL1653146 | 0.75 | LMNA (0.60) | CYP2C9LMNAALDH1A1KMT2ATDP1 | |
| SCHEMBL1653499 | 0.74 | NSD2 (0.61) | LMNAALDH1A1KMT2AMAPTHTT | |
| SCHEMBL10993205 | 0.73 | LMNA (0.65) | CYP2C9CYP2C19LMNAALDH1A1KMT2A | |
| SCHEMBL30958861 | 0.72 | CYP2C9 (0.69) | CYP2C9CYP2C19LMNAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247746-A1 | Fused heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247746-A1 | Fused heterocyclic compound | GCKR, GCK, GPR119 | CYP2C9 565/4885CYP2C19 346/4885LMNA 4417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.