SCHEMBL26689244

SCHEMBL26689244

O=C(O)NCCC(=O)N(CCOC(=O)Oc1ccc([N+](=O)[O-])cc1)CCOC(=O)Oc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ MGLL Q99685 2/20 0.43
▸ HTR2A P28223 1/20 0.42
▸ BCL9 O00512 1/20 0.41
▸ CTNNB1 P35222 1/20 0.41
▸ KMT2A Q03164 2/20 0.41
▸ MEN1 O00255 1/20 0.41
▸ GAA P10253 2/20 0.40
▸ KCNH2 Q12809 3/20 0.40
▸ SMN1; SMN2 Q16637 3/20 0.39
▸ ALDH1A1 P00352 2/20 0.39
▸ LMNA P02545 2/20 0.39
▸ MAPT P10636 7/20 0.39
▸ CRHBP P24387 1/20 0.38
▸ CRHR2 Q13324 1/20 0.38
▸ RAB9A P51151 2/20 0.38
▸ L3MBTL1 Q9Y468 2/20 0.38
▸ NPC1 O15118 1/20 0.38
▸ ATM Q13315 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16322548 0.84 KMT2A (0.52) MGLLHTR2ABCL9CTNNB1KMT2A
SCHEMBL30678099 0.80 KMT2A (0.45) MGLLHTR2ABCL9CTNNB1KMT2A
SCHEMBL26666721 0.80 MGLL (0.47) MGLLHTR2ABCL9CTNNB1KMT2A
SCHEMBL1828761 0.80 MGLL (0.57) MGLLHTR2ABCL9CTNNB1KMT2A
SCHEMBL19027394 0.80 MGLL (0.46) MGLLHTR2ABCL9CTNNB1KMT2A
SCHEMBL21814697 0.79 MGLL (0.46) MGLLHTR2ABCL9CTNNB1KMT2A
SCHEMBL14433148 0.78 GAA (0.51) MGLLHTR2ABCL9CTNNB1KMT2A
SCHEMBL409598 0.76 HTR2A (0.59) MGLLHTR2ABCL9CTNNB1KMT2A
SCHEMBL17087131 0.76 GAA (0.57) MGLLHTR2ABCL9CTNNB1KMT2A
SCHEMBL2735597 0.76 GAA (0.46) MGLLHTR2ABCL9CTNNB1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260061065-A1 ANTIBODY DRUG CONJUGATES NOVARTIS AG (CH) 2026-03-05 — — US disclosed
WO-2023225359-A1 ANTIBODY-DRUG CONJUGATES OF ANTINEOPLASTIC COMPOUNDS AND METHODS OF USE THEREOF NOVARTIS AG (CH) 2023-11-23 — — WO disclosed
WO-2023223097-A1 ANTIBODY DRUG CONJUGATES NOVARTIS AG (CH) 2023-11-23 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260061065-A1 ANTIBODY DRUG CONJUGATES FCGR2A, FCGR3B, BCL3 MGLL 3708/4885HTR2A 3291/4885BCL9 15/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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