Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PDE9A | O76083 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26869219 | 0.84 | PKM (0.41) | PKMSMN1; SMN2LMNAGAABRD4 | |
| SCHEMBL26690789 | 0.78 | PIK3CD (0.41) | PKMSMN1; SMN2LMNAGAAPIK3CD | |
| SCHEMBL16815947 | 0.78 | PKM (0.43) | PKMSMN1; SMN2LMNAGAABRD4 | |
| SCHEMBL16815601 | 0.76 | PKM (0.41) | PKMSMN1; SMN2LMNAGAABRD4 | |
| SCHEMBL26693326 | 0.75 | PKM (0.37) | PKMSMN1; SMN2LMNAGAABRD4 | |
| SCHEMBL26690636 | 0.75 | PKM (0.52) | PKMSMN1; SMN2LMNAGAABRD4 | |
| SCHEMBL12126299 | 0.72 | SMN1; SMN2 (0.43) | PKMSMN1; SMN2LMNAGAABRD4 | |
| SCHEMBL17881937 | 0.72 | GAA (0.43) | PKMSMN1; SMN2GAABRD4CTSK | |
| SCHEMBL27362340 | 0.71 | SIGMAR1 (0.43) | PKMSMN1; SMN2LMNAGAABRD4 | |
| SCHEMBL26869220 | 0.70 | PKM (0.51) | PKMSMN1; SMN2LMNAGAABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023222849-A1 | AMINO HETEROAROMATIC COMPOUNDS USEFUL IN THE TREATMENT OF LIVER DISEASES | ASTRAZENECA AB (SE) | 2023-11-23 | — | — | WO | disclosed |
| WO-2023222849-A1 | AMINO HETEROAROMATIC COMPOUNDS USEFUL IN THE TREATMENT OF LIVER DISEASES | ASTRAZENECA AB (SE) | 2023-11-23 | — | — | WO | disclosed |