Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | STAT1 | P42224 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL522838 | 0.85 | ALDH1A1 (0.57) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL6832741 | 0.85 | TDP1 (0.59) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL18782372 | 0.84 | ALDH1A1 (0.64) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL2146000 | 0.82 | ALDH1A1 (0.54) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL20841712 | 0.82 | ALDH1A1 (0.54) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL22519217 | 0.82 | DHODH (0.56) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL644360 | 0.82 | ALDH1A1 (0.54) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL7511192 | 0.82 | ALDH1A1 (0.54) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL2989798 | 0.81 | MAOB (0.57) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL521687 | 0.81 | ALDH1A1 (0.69) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007122482-A1 | FUSED PHENYL AMIDO HETEROCYCLIC COMPOUNDS FOR THE PREVENTION AND TREATMENT OF GLUCOKINASE-MEDIATED DISEASES | PFIZER PRODUCTS INC. (US) | 2007-11-01 | — | — | WO | disclosed |