Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 12/20 | 0.52 |
| ▸ | GPR183 | P32249 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9071971 | 0.90 | GCK (0.42) | GCK | |
| SCHEMBL2669314 | 0.87 | GCK (0.40) | GCK | |
| SCHEMBL2669283 | 0.87 | GCK (0.66) | GCKHRH3 | |
| SCHEMBL9071954 | 0.86 | GCK (0.48) | GCKGPR183HRH3 | |
| SCHEMBL2643740 | 0.84 | GCK (0.54) | GCKHRH3 | |
| SCHEMBL2669282 | 0.84 | GCK (0.49) | GCKHRH3 | |
| SCHEMBL2669284 | 0.81 | GCK (0.52) | GCKHRH3 | |
| SCHEMBL12101378 | 0.81 | GCK (0.51) | GCKGPR183HRH3 | |
| SCHEMBL644094 | 0.80 | GCK (0.79) | GCK | |
| SCHEMBL15780551 | 0.79 | GCK (0.42) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007122482-A1 | FUSED PHENYL AMIDO HETEROCYCLIC COMPOUNDS FOR THE PREVENTION AND TREATMENT OF GLUCOKINASE-MEDIATED DISEASES | PFIZER PRODUCTS INC. (US) | 2007-11-01 | — | — | WO | disclosed |