Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.48 |
| ▸ | CDK7 | P50613 | 15/20 | 0.47 |
| ▸ | CDK2 | P24941 | 10/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 7/20 | 0.46 |
| ▸ | CCNH | P51946 | 7/20 | 0.46 |
| ▸ | CDK1 | P06493 | 6/20 | 0.46 |
| ▸ | CDK9 | P50750 | 6/20 | 0.46 |
| ▸ | CDK4 | P11802 | 4/20 | 0.46 |
| ▸ | CDK6 | Q00534 | 4/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.46 |
| ▸ | CDK8 | P49336 | 3/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.46 |
| ▸ | CCND1 | P24385 | 2/20 | 0.46 |
| ▸ | INSRR | P14616 | 1/20 | 0.46 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | MAPK15 | Q8TD08 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30716174 | 0.86 | GSK3B (0.53) | KCNN3CDK7CDK2CCNE1CCNH | |
| SCHEMBL18051111 | 0.85 | KCNN3 (0.64) | KCNN3CDK7CDK2CCNE1CCNH | |
| SCHEMBL26696735 | 0.85 | KCNN3 (0.49) | KCNN3CDK7CDK2CCNE1CCNH | |
| SCHEMBL26696755 | 0.84 | KCNN3 (0.51) | KCNN3CDK7CDK2CCNE1CCNH | |
| SCHEMBL18072871 | 0.79 | CDK2 (0.47) | KCNN3CDK7CDK2CCNE1CCNH | |
| SCHEMBL18051011 | 0.77 | CDK9 (0.53) | KCNN3CDK7CDK2CCNE1CCNH | |
| SCHEMBL18050975 | 0.76 | CDK2 (0.45) | KCNN3CDK7CDK2CCNE1CCNH | |
| SCHEMBL26697064 | 0.76 | KCNN3 (0.50) | KCNN3CDK7CDK2CCNE1CCNH | |
| SCHEMBL18050993 | 0.76 | CDK2 (0.44) | KCNN3CDK7CDK2CCNE1CCNH | |
| SCHEMBL30716171 | 0.76 | POLB (0.48) | KCNN3CDK7CDK2CCNE1CCNH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023227125-A1 | NEW FUSED-HETEROCYCLIC COMPOUND AS CDK INHIBITOR AND USE THEREOF | 杭州德睿智药科技有限公司 | 2023-11-30 | — | — | WO | disclosed |