Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 12/20 | 0.42 |
| ▸ | CDK9 | P50750 | 12/20 | 0.42 |
| ▸ | CDK7 | P50613 | 10/20 | 0.42 |
| ▸ | CDK4 | P11802 | 2/20 | 0.42 |
| ▸ | CCNH | P51946 | 8/20 | 0.39 |
| ▸ | MNAT1 | P51948 | 8/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26697025 | 1.00 | CDK2 (0.42) | CDK2CDK9CDK7CDK4CCNH | |
| SCHEMBL26697029 | 0.90 | CDK9 (0.44) | CDK2CDK9CDK7CDK4CCNH | |
| SCHEMBL26697048 | 0.89 | CDK7 (0.48) | CDK2CDK9CDK7CDK4CCNH | |
| SCHEMBL26697043 | 0.89 | CDK7 (0.48) | CDK2CDK9CDK7CDK4CCNH | |
| SCHEMBL26697032 | 0.84 | CDK7 (0.39) | CDK2CDK9CDK7CDK4CCNH | |
| SCHEMBL26697042 | 0.84 | CDK7 (0.39) | CDK2CDK9CDK7CDK4CCNH | |
| SCHEMBL30716320 | 0.81 | CDK2 (0.45) | CDK2CDK9CDK7CDK4CCNH | |
| SCHEMBL26697105 | 0.81 | CDK2 (0.51) | CDK2CDK9CDK7CDK4CCNH | |
| SCHEMBL26696994 | 0.73 | CDK2 (0.32) | CDK2CDK9CDK7CDK4 | |
| SCHEMBL26696975 | 0.73 | CDK2 (0.32) | CDK2CDK9CDK7CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023227125-A1 | NEW FUSED-HETEROCYCLIC COMPOUND AS CDK INHIBITOR AND USE THEREOF | 杭州德睿智药科技有限公司 | 2023-11-30 | — | — | WO | disclosed |