Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 14/20 | 0.45 |
| ▸ | CDK9 | P50750 | 14/20 | 0.45 |
| ▸ | CDK7 | P50613 | 7/20 | 0.43 |
| ▸ | CDK4 | P11802 | 2/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.40 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
| ▸ | CLK3 | P49761 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | CCNH | P51946 | 5/20 | 0.38 |
| ▸ | MNAT1 | P51948 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30716232 | 0.87 | CDK2 (0.49) | CDK2CDK9CDK7CDK4CDK5 | |
| SCHEMBL26697019 | 0.81 | CDK2 (0.42) | CDK2CDK9CDK7CDK4CCNH | |
| SCHEMBL26697025 | 0.81 | CDK2 (0.42) | CDK2CDK9CDK7CDK4CCNH | |
| SCHEMBL30716295 | 0.81 | CDK2 (0.41) | CDK2CDK9CDK7CDK4CCNH | |
| SCHEMBL30716245 | 0.80 | CDK2 (0.56) | CDK2CDK9CDK7CDK4CDK5 | |
| SCHEMBL26696894 | 0.77 | CDK2 (0.39) | CDK2CDK9CDK7CDK5CDK5R1 | |
| SCHEMBL30716316 | 0.73 | CDK7 (0.66) | CDK2CDK9CDK7CCNHMNAT1 | |
| SCHEMBL30716251 | 0.72 | CDK2 (0.42) | CDK2CDK9CDK7CDK4CDK5 | |
| SCHEMBL26697029 | 0.70 | CDK9 (0.44) | CDK2CDK9CDK7CDK4CCNH | |
| SCHEMBL26697043 | 0.69 | CDK7 (0.48) | CDK2CDK9CDK7CDK4CCNH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023227125-A1 | NEW FUSED-HETEROCYCLIC COMPOUND AS CDK INHIBITOR AND USE THEREOF | 杭州德睿智药科技有限公司 | 2023-11-30 | — | — | WO | disclosed |