Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | PREP | P48147 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25866607 | 0.77 | CHRM2 (0.41) | HPGDEPHX1HSD17B10GRIN2BGRIN2C | |
| SCHEMBL30716372 | 0.76 | HPGD (0.40) | HPGDEPHX1HSD17B10GRIN2BGRIN2C | |
| SCHEMBL8667004 | 0.73 | GPR119 (0.43) | MEN1KMT2A | |
| SCHEMBL28170943 | 0.73 | CHRM2 (0.37) | HPGDEPHX1GRIN2BGRIN2CCHRM2 | |
| SCHEMBL21996524 | 0.73 | HPGD (0.40) | HPGDEPHX1ALDH1A1MAPTCHRM2 | |
| SCHEMBL29057889 | 0.73 | HSD17B10 (0.41) | HPGDEPHX1HSD17B10ALDH1A1MEN1 | |
| SCHEMBL28907155 | 0.73 | HPGD (0.40) | HPGDEPHX1HSD17B10GRIN2BGRIN2C | |
| SCHEMBL22047542 | 0.73 | HPGD (0.40) | HPGDEPHX1ALDH1A1MAPTCHRM2 | |
| SCHEMBL31472701 | 0.72 | MEN1 (0.43) | HPGDEPHX1HSD17B10ALDH1A1MEN1 | |
| SCHEMBL30716242 | 0.72 | CHRM2 (0.40) | HPGDEPHX1HSD17B10GRIN2BGRIN2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023227125-A1 | NEW FUSED-HETEROCYCLIC COMPOUND AS CDK INHIBITOR AND USE THEREOF | 杭州德睿智药科技有限公司 | 2023-11-30 | — | — | WO | disclosed |