Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 9/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8667000 | 0.80 | RORC (0.44) | GPR119RORCKDM4EPKMUSP30 | |
| SCHEMBL27851932 | 0.77 | TSHR (0.42) | GPR119RORCNR1H2NR1H3MEN1 | |
| SCHEMBL28809336 | 0.76 | GPR119 (0.42) | GPR119RORCNR1H2NR1H3KDM4E | |
| SCHEMBL18642718 | 0.74 | NR1H2 (0.53) | GPR119RORCNR1H2NR1H3ALOX15 | |
| SCHEMBL16004573 | 0.74 | NR1H2 (0.53) | GPR119RORCNR1H2NR1H3ALOX15 | |
| SCHEMBL28815574 | 0.74 | NR1H2 (0.53) | GPR119RORCNR1H2NR1H3ALOX15 | |
| SCHEMBL26697109 | 0.73 | HPGD (0.38) | MEN1KMT2A | |
| SCHEMBL20574279 | 0.73 | TACR1 (0.41) | GPR119RORCNR1H2NR1H3KDM4E | |
| SCHEMBL15664940 | 0.73 | TSHR (0.43) | GPR119RORCNR1H2NR1H3ALOX15 | |
| SCHEMBL27952441 | 0.73 | TSHR (0.43) | GPR119RORCNR1H2NR1H3ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0856002-A1 | PHENYLOXAZOLIDINONES HAVING A C-C BOND TO 4-8 MEMBERED HETEROCYCLIC RINGS | PHARMACIA & UPJOHN COMPANY (US) | 1998-08-05 | — | — | EP | disclosed |
| WO-1997009328-A1 | PHENYLOXAZOLIDINONES HAVING A C-C BOND TO 4-8 MEMBERED HETEROCYCLIC RINGS | PHARMACIA & UPJOHN COMPANY (US) | 1997-03-13 | — | — | WO | disclosed |