Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KHK | P50053 | 1/20 | 0.42 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2419004 | 0.81 | KHK (0.46) | KHKTRPV4XDHADRB2ADRB1 | |
| SCHEMBL10474259 | 0.76 | KHK (0.42) | KHKTRPV4XDHADRB2ADRB1 | |
| SCHEMBL10723421 | 0.76 | KHK (0.42) | KHKTRPV4CYP11B1CYP11B2 | |
| SCHEMBL2655367 | 0.73 | TRPV4 (0.39) | KHKTRPV4XDHCYP11B1CYP11B2 | |
| SCHEMBL30699649 | 0.73 | CA1 (0.38) | — | |
| SCHEMBL19769015 | 0.72 | ADRB2 (0.41) | KHKTRPV4ADRB2ADRB1CYP11B1 | |
| SCHEMBL22096848 | 0.72 | KHK (0.39) | KHKTRPV4ADRB2ADRB1CYP11B1 | |
| SCHEMBL21685744 | 0.72 | CA1 (0.32) | — | |
| SCHEMBL809090 | 0.69 | TRPV4 (0.48) | KHKTRPV4CYP11B1CYP11B2 | |
| SCHEMBL31588414 | 0.69 | TRPV4 (0.48) | KHKTRPV4CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023227080-A1 | PROTAC COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 百极弘烨(南通)医药科技有限公司 | 2023-11-30 | — | — | WO | disclosed |