Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 9/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31417771 | 0.84 | FAAH (0.55) | FAAHKMT2AGAAKDM4EBLM | |
| SCHEMBL26697229 | 0.82 | KMT2A (0.54) | KMT2AGAAKDM4EBLMALDH1A1 | |
| SCHEMBL31417619 | 0.76 | FAAH (0.56) | FAAHKMT2AGAAKDM4EBLM | |
| SCHEMBL9124655 | 0.75 | TRPV1 (0.60) | KMT2AGAAKDM4EBLMALDH1A1 | |
| SCHEMBL28688217 | 0.75 | FAAH (0.62) | FAAHKMT2AGAAKDM4EBLM | |
| SCHEMBL28081709 | 0.74 | TSHR (0.37) | FAAHALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL28180607 | 0.73 | ALDH1A1 (0.57) | FAAHKMT2AGAAKDM4EALDH1A1 | |
| SCHEMBL26697273 | 0.73 | NPC1 (0.61) | KMT2AGAAKDM4EALDH1A1HTT | |
| SCHEMBL27663187 | 0.72 | FAAH (0.52) | FAAHKMT2AGAAKDM4EBLM | |
| SCHEMBL24272365 | 0.72 | SMN1; SMN2 (0.74) | KMT2AGAAKDM4EALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023226323-A1 | QUINAZOLINE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 天津济坤医药科技有限公司 | 2023-11-30 | — | — | WO | disclosed |