Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 2/20 | 0.34 |
| ▸ | CFTR | P13569 | 2/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9070776 | 0.87 | KMT2A (0.37) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2669943 | 0.80 | GCGR (0.44) | APPRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL2669784 | 0.78 | NAMPT (0.33) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2669825 | 0.76 | NPC1 (0.46) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2669990 | 0.73 | GCGR (0.43) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2669951 | 0.71 | GCGR (0.45) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL717999 | 0.71 | GCGR (0.47) | APPRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL2669993 | 0.70 | GCGR (0.41) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2669950 | 0.70 | GCGR (0.41) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2669940 | 0.70 | NPC1 (0.36) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110520-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-09-11 | — | — | WO | disclosed |