Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 7/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.30 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.30 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.30 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.30 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.30 |
| ▸ | GCGR | P47871 | 1/20 | 0.30 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.30 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2669899 | 0.82 | NAMPT (0.36) | NAMPTABCB11CYP3A4ADRA2BOPRD1 | |
| SCHEMBL2669810 | 0.81 | NAMPT (0.34) | NAMPTSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL2669818 | 0.78 | APP (0.39) | NAMPTSMN1; SMN2HDAC3HDAC1HDAC2 | |
| SCHEMBL9070773 | 0.77 | GCG (0.42) | NAMPTMEN1KMT2AADCY6ADCY3 | |
| SCHEMBL2669941 | 0.74 | TP53 (0.36) | NAMPTSMN1; SMN2HDAC3HDAC1MEN1 | |
| SCHEMBL2669990 | 0.72 | GCGR (0.43) | SMN1; SMN2MEN1KMT2AADCY6ADCY3 | |
| SCHEMBL718824 | 0.70 | GCG (0.42) | GCGRNPC1RAB9A | |
| SCHEMBL718723 | 0.70 | MEN1 (0.44) | MEN1KMT2ANPC1RAB9A | |
| SCHEMBL2669943 | 0.69 | GCGR (0.44) | CYP3A4SMN1; SMN2ADCY6ADCY3ADCY9 | |
| SCHEMBL2669940 | 0.69 | NPC1 (0.36) | NAMPTSMN1; SMN2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110520-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-09-11 | — | — | WO | disclosed |