SCHEMBL968516

SCHEMBL968516

CCC(=O)Oc1ccc(C(=O)Cl)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 10/20 0.70
SMN1; SMN2 Q16637 4/20 0.70
ESR1 P03372 2/20 0.70
HIF1A Q16665 2/20 0.70
RECQL P46063 1/20 0.70
ELANE P08246 1/20 0.64
MAPT P10636 5/20 0.48
NPC1 O15118 3/20 0.48
RAB9A P51151 3/20 0.48
ACHE P22303 2/20 0.46
HTT P42858 3/20 0.46
MEN1 O00255 1/20 0.46
ALDH1A1 P00352 3/20 0.46
HSD17B10 Q99714 2/20 0.46
LMNA P02545 1/20 0.46
KDM4E B2RXH2 2/20 0.45
PKM P14618 1/20 0.45
USP2 O75604 1/20 0.44
GLA P06280 1/20 0.44
GAA P10253 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL312147 0.85 KMT2A (0.76) KMT2ASMN1; SMN2ESR1HIF1ARECQL
SCHEMBL6563870 0.85 BCL9 (0.57) KMT2ASMN1; SMN2ESR1HIF1ARECQL
SCHEMBL11445596 0.83 KMT2A (0.73) KMT2ASMN1; SMN2ESR1HIF1ARECQL
SCHEMBL5690655 0.82 KMT2A (0.72) KMT2ASMN1; SMN2ESR1HIF1ARECQL
Diethylstilbestrol Dipropionate SCHEMBL151730 0.82 KMT2A (1.00) KMT2ASMN1; SMN2ESR1HIF1ARECQL
Diethylstilbestrol Dipropionate SCHEMBL2440005 0.82 KMT2A (1.00) KMT2ASMN1; SMN2ESR1HIF1ARECQL
SCHEMBL11374349 0.82 KMT2A (0.72) KMT2ASMN1; SMN2ESR1HIF1ARECQL
SCHEMBL11655934 0.81 HIF1A (0.66) KMT2ASMN1; SMN2ESR1HIF1ARECQL
SCHEMBL11115353 0.81 KMT2A (0.55) KMT2ASMN1; SMN2ESR1HIF1ARECQL
SCHEMBL26698255 0.81 KMT2A (0.70) KMT2ASMN1; SMN2ESR1HIF1ARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009584-A1 Romp-Polymerizable Electron Transport Materials Based On A Bis-Oxadiazole Moiety GEORGIA TECH RESEARCH CORPORATION (US) 2011-01-13 US disclosed
EP-2234991-A1 ROMP-POLYMERIZABLE ELECTRON TRANSPORT MATERIALS BASED ON A BIS-OXADIAZOLE MOIETY Georgia Tech Research Corporation (US) 2010-10-06 EP disclosed
WO-2009080797-A1 ROMP-POLYMERIZABLE ELECTRON TRANSPORT MATERIALS BASED ON A BIS-OXADIAZOLE MOIETY GEORGIA TECH RESEARCH CORPORATION (US) 2009-07-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009584-A1 Romp-Polymerizable Electron Transport Materials Based On A Bis-Oxadiazole Moiety SLCO1B3, SLCO4C1, SLCO2B1 KMT2A 4680/4885SMN1; SMN2 2957/4885ESR1 411/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.