SCHEMBL26698256

SCHEMBL26698256

NC(=O)OCCN1CCNCC1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
KDM4E B2RXH2 4/20 0.40
ALDH1A1 P00352 4/20 0.40
TDP1 Q9NUW8 2/20 0.40
MAPT P10636 1/20 0.40
SIGMAR1 Q99720 2/20 0.39
CHRM2 P08172 1/20 0.39
CHRM4 P08173 1/20 0.39
CHRM5 P08912 1/20 0.39
CHRM1 P11229 1/20 0.39
CHRM3 P20309 1/20 0.39
POLB P06746 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HSD17B10 Q99714 1/20 0.38
ANPEP P15144 1/20 0.37
ERAP2 Q6P179 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28927077 0.90 MEN1 (0.48) MEN1KMT2AKDM4EALDH1A1TDP1
SCHEMBL8814790 0.89 CXCR4 (0.43) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL22266346 0.87 CXCR4 (0.44) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL28927092 0.86 CXCR4 (0.47) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL9423512 0.84 MEN1 (0.46) MEN1KMT2AKDM4EALDH1A1TDP1
Trifluoroacetic Acid SCHEMBL9127928 0.84 CXCR4 (0.41) MEN1KMT2AKDM4EALDH1A1TDP1
SCHEMBL9423515 0.82 MEN1 (0.45) MEN1KMT2AKDM4EALDH1A1TDP1
SCHEMBL167666 0.82 L3MBTL1 (0.52) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL8693568 0.81 MEN1 (0.42) MEN1KMT2AKDM4EALDH1A1TDP1
SCHEMBL5953471 0.81 SLC18A3 (0.49) MEN1KMT2AKDM4EALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025064718-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-27 WO disclosed
WO-2023226965-A1 ROCK INHIBITORS AND USES THEREOF DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) 2023-11-30 WO disclosed
CN-116391129-A Target binding assays for RAS proteins 普罗美加公司 2023-07-04 CN disclosed
CN-112739343-A Macrocyclic MCL-1 inhibitors and methods of use 艾伯维公司 2021-04-30 CN disclosed
CN-112533598-A Macrocyclic MCL-1 inhibitors and methods of use 艾伯维公司 2021-03-19 CN disclosed