Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5093580 | 0.98 | L3MBTL1 (0.55) | L3MBTL1KMT2AMEN1HPGDMAPT | |
| SCHEMBL4574027 | 0.89 | KMT2A (0.53) | KMT2AMEN1HPGDBCHESIGMAR1 | |
| SCHEMBL31243628 | 0.86 | CYP2D6 (0.54) | L3MBTL1KMT2AMEN1MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL7396009 | 0.84 | CYP2D6 (0.53) | L3MBTL1KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL2686485 | 0.84 | HRH3 (0.50) | L3MBTL1KMT2AMEN1ALDH1A1HRH1 | |
| SCHEMBL4807116 | 0.84 | HRH3 (0.50) | L3MBTL1KMT2AMEN1ALDH1A1HRH1 | |
| SCHEMBL9043762 | 0.84 | KMT2A (0.38) | L3MBTL1KMT2AMEN1HPGDBCHE | |
| SCHEMBL29025304 | 0.83 | ALDH1A1 (0.41) | L3MBTL1KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL9980789 | 0.83 | ALDH1A1 (0.49) | ALDH1A1CHRM2CHRM4HTR1ACHRM5 | |
| SCHEMBL167209 | 0.82 | KMT2A (0.51) | L3MBTL1KMT2AMEN1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104080335-B | Some chemical entities, composition and method | 钱向平 | 2017-06-09 | — | — | CN | claimed |
| CN-104427873-A | Certain chemical entities, compositions, and methods | NEUPHARMA INC | 2015-03-18 | — | — | CN | claimed |
| CN-104080335-A | Certain chemical entities, compositions, and methods | QIAN XIANGPING | 2014-10-01 | — | — | CN | claimed |
| CN-103880862-A | Inhibitors Of Hepatitis C Virus Replication | MERCK SHARP & DOHME | 2014-06-25 | — | — | CN | claimed |
| CN-102427729-A | Inhibitors of hepatitis c virus replication | MERCK SHARP & DOHME | 2012-04-25 | — | — | CN | claimed |
| WO-2012027957-A1 | BUFALIN DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USE THEREOF | SUZHOU NEUPHARMA CO., LTD. (CN) | 2012-03-08 | — | — | WO | claimed |
| CN-119698406-A | Nanomaterials comprising triols | 比姆医疗股份有限公司 | 2025-03-25 | — | — | CN | disclosed |
| CN-116761888-A | Nanomaterial for the preparation of a nanoparticle | 比姆医疗股份有限公司 | 2023-09-15 | — | — | CN | disclosed |
| CN-108276382-B | Cyclin-dependent kinase inhibitor and application thereof | 南京圣和药物研发有限公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-113423711-A | Thieno [3,2-B ] pyridine derivatives as UDP glycosyltransferase inhibitors and methods of use thereof | 建新公司 | 2021-09-21 | — | — | CN | disclosed |
| CN-107973791-B | Fused or tricyclic aryl pyrimidine compounds as kinase inhibitors | 南京圣和药业股份有限公司 | 2020-04-07 | — | — | CN | disclosed |
| CN-107614503-B | Fused or tricyclic aryl pyrimidine compounds as kinase inhibitors | 广东众生药业股份有限公司 | 2020-03-10 | — | — | CN | disclosed |
| WO-2019190259-A1 | NOVEL SULFONAMIDE DERIVATIVE HAVING INHIBITORY EFFECT ON EPIDERMAL GROWTH FACTOR RECEPTOR MUTATION | 한미약품 주식회사 | 2019-10-03 | — | — | WO | disclosed |
| CN-107614503-A | Fused or tricyclic aryl pyrimidine compounds as kinase inhibitors | 广东众生药业股份有限公司 | 2018-01-19 | — | — | CN | disclosed |
| CN-104080335-B | Some chemical entities, composition and method | 钱向平 | 2017-06-09 | — | — | CN | disclosed |
| CN-103980338-B | Bufalin derivatives, pharmaceutical compositions and methods thereof | 苏州润新生物科技有限公司 | 2017-04-26 | — | — | CN | disclosed |
| CN-103980337-B | Bufalin derivant, its pharmaceutical composition and purposes | 苏州润新生物科技有限公司 | 2016-08-24 | — | — | CN | disclosed |
| CN-104427873-A | Certain chemical entities, compositions, and methods | NEUPHARMA INC | 2015-03-18 | — | — | CN | disclosed |
| CN-104080335-A | Certain chemical entities, compositions, and methods | QIAN XIANGPING | 2014-10-01 | — | — | CN | disclosed |
| CN-102427729-A | Inhibitors of hepatitis c virus replication | MERCK SHARP & DOHME | 2012-04-25 | — | — | CN | disclosed |