Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28460581 | 0.90 | SMN1; SMN2 (0.59) | MAPTL3MBTL1LMNAALDH1A1HDAC1 | |
| SCHEMBL8593356 | 0.89 | TDP1 (0.60) | TDP1MAPTL3MBTL1LMNANR4A2 | |
| SCHEMBL7716363 | 0.84 | TDP1 (0.57) | TDP1MAPTL3MBTL1LMNANR4A2 | |
| SCHEMBL7716366 | 0.84 | TDP1 (0.57) | TDP1MAPTL3MBTL1LMNANR4A2 | |
| SCHEMBL6935004 | 0.82 | TDP1 (0.68) | TDP1MAPTL3MBTL1LMNANR4A2 | |
| SCHEMBL27687045 | 0.82 | MAPT (0.58) | TDP1MAPTL3MBTL1LMNANR4A2 | |
| SCHEMBL23169197 | 0.81 | L3MBTL1 (0.61) | TDP1MAPTL3MBTL1LMNANR4A2 | |
| SCHEMBL8896075 | 0.81 | MAPT (0.53) | TDP1MAPTL3MBTL1LMNANR4A2 | |
| SCHEMBL16451430 | 0.81 | TDP1 (0.54) | TDP1MAPTL3MBTL1LMNANR4A2 | |
| SCHEMBL2010553 | 0.81 | L3MBTL1 (0.53) | TDP1MAPTL3MBTL1LMNANR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023226965-A1 | ROCK INHIBITORS AND USES THEREOF | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2023-11-30 | — | — | WO | disclosed |
| CN-109096150-B | Method for preparing beta-aminoketone by photoinduction nonmetal catalysis | 中国科学技术大学 | 2020-08-25 | — | — | CN | disclosed |