SCHEMBL2010553

SCHEMBL2010553

CC(=O)OCCC(=O)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.53
TDP1 Q9NUW8 4/20 0.53
MAPT P10636 4/20 0.53
LMNA P02545 3/20 0.53
NR4A2 P43354 1/20 0.53
KMT2A Q03164 5/20 0.52
ALDH1A1 P00352 4/20 0.50
GAA P10253 1/20 0.48
CYP2C19 P33261 1/20 0.48
HDAC3 O15379 1/20 0.48
HDAC4 P56524 1/20 0.48
HDAC1 Q13547 1/20 0.48
HDAC7 Q8WUI4 1/20 0.48
HDAC2 Q92769 1/20 0.48
HDAC10 Q969S8 1/20 0.48
HDAC11 Q96DB2 1/20 0.48
HDAC8 Q9BY41 1/20 0.48
HDAC6 Q9UBN7 1/20 0.48
HDAC9 Q9UKV0 1/20 0.48
HDAC5 Q9UQL6 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2797428 0.89 TDP1 (0.60) L3MBTL1TDP1MAPTLMNANR4A2
SCHEMBL25413887 0.87 TDP1 (0.63) L3MBTL1TDP1MAPTLMNANR4A2
SCHEMBL7716363 0.84 TDP1 (0.57) L3MBTL1TDP1MAPTLMNANR4A2
SCHEMBL7716366 0.84 TDP1 (0.57) L3MBTL1TDP1MAPTLMNANR4A2
SCHEMBL27687045 0.82 MAPT (0.58) L3MBTL1TDP1MAPTLMNANR4A2
SCHEMBL6935004 0.82 TDP1 (0.68) L3MBTL1TDP1MAPTLMNANR4A2
SCHEMBL2749745 0.81 NPC1 (0.58) MAPTLMNAKMT2AMEN1SMN1; SMN2
SCHEMBL5708597 0.81 ALDH1A1 (0.47) TDP1MAPTLMNAKMT2AALDH1A1
SCHEMBL28689137 0.81 L3MBTL1 (0.50) L3MBTL1TDP1MAPTLMNANR4A2
SCHEMBL7145858 0.81 MAPT (0.45) L3MBTL1MAPTKMT2AALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114059114-B Cyanide-free low-temperature black tin-nickel alloy electroplating solution and electroplating process 厦门华弘昌科技有限公司 2023-02-10 CN claimed
CN-114059114-A Cyanide-free low-temperature black tin-nickel alloy electroplating solution and electroplating process 厦门华弘昌科技有限公司 2022-02-18 CN claimed
CN-111542736-B Temperature detecting material and estimation system for temperature deviation time using the same 株式会社日立产机系统 2023-08-29 CN disclosed
CN-114950558-B Bipiperidine skeleton tetradentate nitrogen-containing manganese catalyst and method for catalyzing hydrocarbon molecule benzyl site selective oxidation by using same 陕西师范大学 2023-08-11 CN disclosed
CN-115436510-A Method for identifying difference of flavor compounds in livestock and poultry meat based on gas chromatography-electrostatic field orbit trap high-resolution mass spectrometry 中国农业科学院北京畜牧兽医研究所 2022-12-06 CN disclosed
CN-114950558-A Bipiperidine skeleton tetradentate nitrogen-containing manganese catalyst and method for catalyzing benzyl-site selective oxidation of hydrocarbon molecules by using same 陕西师范大学 2022-08-30 CN disclosed
CN-114933543-A Synthetic method of 3-cyclopropylamino-2- (2, 4-dichloro-5-fluorobenzoyl) methyl acrylate 山东国邦药业有限公司 2022-08-23 CN disclosed
CN-110678170-A Pullulan polysaccharide capsule 比利时胶囊公司 2020-01-10 CN disclosed
US-10253205-B2 Aqueous composition for forming a hardcoat layer and hardcoat layer FUJIFILM CORPORATION (JP) 2019-04-09 US disclosed
US-20160017173-A1 AQUEOUS COMPOSITION FOR FORMING A HARDCOAT LAYER AND HARDCOAT LAYER FUJIFILM CORPORATION (JP) 2016-01-21 US disclosed
US-9223211-B2 Photosensitive resin compositions, processes for preparing cured films, the resulting cured films, organic EL display devices and liquid crystal display devices FUJIFILM CORPORATION (JP) 2015-12-29 US disclosed
WO-2006122788-A1 DERIVATIVES OF 4-(2-AMINO-1-HYDROXYETHYL)PHENOL AS AGONISTS OF THE β2 ADRENERGIC RECEPTOR LABORATORIOS ALMIRALL, S.A. (ES) 2006-11-23 WO disclosed
US-20050014942-A1 Transforming growth factor inhibitor; controllign cell differentiation, cell proliferation NIPPON SHINYAKU CO., LTD. (JP) 2005-01-20 US disclosed
EP-1452525-A1 AMIDE DERIVATIVES AND DRUGS Nippon Shinyaku Co., Ltd. (JP) 2004-09-01 EP disclosed
US-5670563-A ORGANOTIN COMPOUND, PHOSPHORUS COMPOUND CIBA-SPECIALTY CHEMICALS CORPORATION (US) 1997-09-23 US disclosed
EP-0542300-B1 Method of preparing (S)-1-phenyl-1,3-propanediol or derivatives thereof AJINOMOTO KK (JP) 1997-02-26 EP disclosed
US-5393664-A Using a culture product AJINOMOTO CO. INC. (JP) 1995-02-28 US disclosed
EP-0542300-A2 Method of preparing (S)-1-phenyl-1,3-propanediol or derivatives thereof Ajinomoto Co., Inc. (JP) 1993-05-19 EP disclosed
US-4958021-A PRESSURE AND HEAT SENSITIVE RECORDING MATERIALS BASF AKTIENGESELLSCHAFT (DE) 1990-09-18 US disclosed
US-4022773-A 7-ACYLAMINO-3-SUBSTITUTED-3-CEPHEM-4-CARBOXYLIC ACIDS, 1-OXIDES ISHIMARU TOSHIYASU 1977-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050014942-A1 Transforming growth factor inhibitor; controllign cell differentiation, cell proliferation TGFBR1, TGFBR2, TGFB1 L3MBTL1 1514/4885TDP1 4752/4885MAPT 4750/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.