SCHEMBL2669833 — predicted protein targets

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	CYP4F2	P78329	1/20	0.39

▸	CYP4A11	Q02928	1/20	0.39

▸	GPR132	Q9UNW8	9/20	0.38

▸	PLG	P00747	1/20	0.35

▸	IGLV6-57	P01721	1/20	0.35

▸	GCG	P01275	1/20	0.35

▸	LMNA	P02545	1/20	0.35

▸	RECQL	P46063	1/20	0.35

▸	PTAFR	P25105	2/20	0.35

▸	MAPT	P10636	1/20	0.34

▸	ALOX5	P09917	1/20	0.34

▸	PPARG	P37231	1/20	0.34

▸	PSEN1	P49768	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL2669958	0.93	CASP3 (0.39)	CYP4F2CYP4A11
SCHEMBL2669819	0.92	CYP4F2 (0.36)	CYP4F2CYP4A11GCGMAPT
SCHEMBL2669904	0.90	CYP4F2 (0.34)	CYP4F2CYP4A11GCGMAPT
SCHEMBL13069673	0.89	CYP4F2 (0.36)	CYP4F2CYP4A11GCGLMNA
SCHEMBL2669782	0.88	EGFR (0.36)	CYP4F2CYP4A11GCG
SCHEMBL9070778	0.86	PTGS2 (0.42)	CYP4F2CYP4A11GCG
SCHEMBL2669939	0.86	NPC1 (0.39)	—
SCHEMBL2669836	0.85	NPC1 (0.33)	GCG
SCHEMBL9070786	0.85	NPC1 (0.37)	—
SCHEMBL2669955	0.84	ESR1 (0.39)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2009110520-A1	HETEROCYCLIC COMPOUND	武田薬品工業株式会社 (JP)	2009-09-11	—	—	WO	disclosed