Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCG | P01275 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.32 |
| ▸ | GSK3B | P49841 | 2/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.31 |
| ▸ | WNT1 | P04628 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2669960 | 0.89 | GCG (0.40) | GCGMEN1TP53TSHRHTT | |
| SCHEMBL2669953 | 0.86 | BTK (0.41) | GCGBTKGCGR | |
| SCHEMBL2669769 | 0.84 | NAMPT (0.36) | GCGMEN1TP53TSHRHTT | |
| SCHEMBL9070790 | 0.83 | NAMPT (0.34) | GCGMEN1TP53TSHRHTT | |
| SCHEMBL2669895 | 0.82 | ESR1 (0.42) | MEN1TP53TSHRHTTKMT2A | |
| SCHEMBL2669898 | 0.82 | MAPT (0.38) | NPC1RAB9AMEN1TP53TSHR | |
| SCHEMBL2669989 | 0.81 | NAMPT (0.35) | MEN1TP53TSHRHTTKMT2A | |
| SCHEMBL2669961 | 0.81 | MEN1 (0.35) | GCGNPC1RAB9AMEN1TP53 | |
| SCHEMBL718744 | 0.81 | BTK (0.38) | GCGBTKPIM1PIM2LRRK2 | |
| SCHEMBL13069831 | 0.80 | NPC1 (0.33) | NPC1RAB9AMEN1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110520-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-09-11 | — | — | WO | disclosed |