SCHEMBL26698709

SCHEMBL26698709

Nc1cc(-c2ccccc2)c(N)c(N)c1N.Nc1ccc(-c2ccc(N)c(N)c2)cc1N

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
HSD17B10 Q99714 5/20 0.44
MAPT P10636 4/20 0.44
ALDH1A1 P00352 3/20 0.44
ALOX15 P16050 3/20 0.44
KDM4E B2RXH2 2/20 0.44
GAA P10253 2/20 0.44
USP2 O75604 1/20 0.44
LMNA P02545 1/20 0.44
HSP90AA1 P07900 1/20 0.44
HPGD P15428 1/20 0.44
ALOX12 P18054 1/20 0.44
HTT P42858 1/20 0.44
IKBKB O14920 1/20 0.40
KCNH2 Q12809 2/20 0.39
PDE4A P27815 1/20 0.38
PDE4B Q07343 1/20 0.38
PDE4C Q08493 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL560129 0.88 ALDH1A1 (0.52) MEN1KMT2ATDP1HSD17B10MAPT
SCHEMBL29367789 0.88 ALDH1A1 (0.52) MEN1KMT2ATDP1HSD17B10MAPT
Methane SCHEMBL22720569 0.86 ALDH1A1 (0.50) MEN1KMT2ATDP1HSD17B10MAPT
Water SCHEMBL6229709 0.86 HSD17B10 (0.50) MEN1KMT2ATDP1HSD17B10MAPT
Hydrogen Sulfide SCHEMBL6229946 0.86 ALDH1A1 (0.50) MEN1KMT2ATDP1HSD17B10MAPT
Hydrochloric Acid SCHEMBL4521255 0.86 HSD17B10 (0.50) MEN1KMT2ATDP1HSD17B10MAPT
SCHEMBL653071 0.80 TDP1 (0.74) MEN1KMT2ATDP1HSD17B10MAPT
SCHEMBL30392415 0.80 TDP1 (0.74) MEN1KMT2ATDP1HSD17B10MAPT
SCHEMBL27829121 0.80 TDP1 (0.74) MEN1KMT2ATDP1HSD17B10MAPT
SCHEMBL5703627 0.79 MEN1 (0.43) MEN1KMT2ATDP1HSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230387548-A1 Heat/Flame-Resistant Polymer Composite-Based Solid Electrolyte Separator, Lithium Secondary Battery, and Manufacturing Method GLOBAL GRAPHENE GROUP, INC. (US) 2023-11-30 US disclosed