SCHEMBL653071

SCHEMBL653071

Nc1ccc(-c2ccccc2)cc1N

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.74
MEN1 O00255 2/20 0.74
KMT2A Q03164 2/20 0.74
HSD17B10 Q99714 4/20 0.64
ALDH1A1 P00352 4/20 0.64
ALOX15 P16050 3/20 0.64
MAPT P10636 2/20 0.64
KDM4E B2RXH2 1/20 0.64
USP2 O75604 1/20 0.64
LMNA P02545 1/20 0.64
HSP90AA1 P07900 1/20 0.64
GAA P10253 1/20 0.64
HPGD P15428 1/20 0.64
ALOX12 P18054 1/20 0.64
HTT P42858 1/20 0.64
IKBKB O14920 1/20 0.55
CYP3A4 P08684 4/20 0.55
TAAR1 Q96RJ0 1/20 0.55
MAOA P21397 1/20 0.54
KCNH2 Q12809 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30392415 1.00 TDP1 (0.74) TDP1MEN1KMT2AHSD17B10ALDH1A1
SCHEMBL27829121 1.00 TDP1 (0.74) TDP1MEN1KMT2AHSD17B10ALDH1A1
Methane SCHEMBL27562098 0.97 MEN1 (0.70) TDP1MEN1KMT2AHSD17B10ALDH1A1
Water SCHEMBL3120549 0.97 TDP1 (0.70) TDP1MEN1KMT2AHSD17B10ALDH1A1
Formaldehyde SCHEMBL27638408 0.93 KMT2A (0.64) TDP1MEN1KMT2AHSD17B10ALDH1A1
SCHEMBL28056500 0.93 TDP1 (0.64) TDP1MEN1KMT2AHSD17B10ALDH1A1
Sulfur Dioxide SCHEMBL29028945 0.91 KMT2A (0.61) TDP1MEN1KMT2AHSD17B10ALDH1A1
SCHEMBL12772920 0.89 TDP1 (0.93) TDP1MEN1KMT2AHSD17B10ALDH1A1
Hydrochloric Acid SCHEMBL1646515 0.86 TDP1 (0.88) TDP1MEN1KMT2AHSD17B10ALDH1A1
Hydrogen Peroxide SCHEMBL2904527 0.86 TDP1 (0.88) TDP1MEN1KMT2AHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 294 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118184603-A Diamine monomer containing piperazine unit, polyimide acid salt separation membrane, and preparation method and application thereof 天津科技大学 2024-06-14 CN claimed
CN-117659787-A Preparation method of soluble polyimide/acrylic acid ionic crosslinking type antifouling coating 兰州大学 2024-03-08 CN claimed
CN-113963959-B Preparation method of polyaniline long-and-short-chain composite electrode material and application of polyaniline long-and-short-chain composite electrode material in construction of wide-voltage super capacitor 合肥工业大学 2023-02-24 CN claimed
CN-113737310-A Graphene polyimide composite fiber and preparation method thereof 南通强生石墨烯科技有限公司 2021-12-03 CN claimed
US-20210285939-A1 ELECTROPOLYMERIZED ALLERGEN DETECTION DEVICE AND METHODS OF USE THEREOF Allergy Amulet, Inc. (US) 2021-09-16 US claimed
EP-3874268-A2 ELECTROPOLYMERIZED ALLERGEN DETECTION DEVICE AND METHODS OF USE THEREOF Allergy Amulet, Inc. (US) 2021-09-08 EP claimed
CN-110220997-A A kind of method of antioxidant in the detection flesh of fish 哈尔滨学院 2019-09-10 CN claimed
CN-109851032-A A kind of method of schiff bases copper complex catalyzing hydrogen peroxide oxidative degradation triclosan 河南师范大学 2019-06-07 CN claimed
CN-106083727-B A kind of mixing-in fat base bis- (benzimidazole hyamines) and the preparation method and application thereof 广东工业大学 2019-04-19 CN claimed
CN-108558885-A A kind of includes the synthetic method of the dihydro azepine of adjacent diaminophenazine structure and benzene-like compounds 兰州大学 2018-09-21 CN claimed
WO-2017051353-A1 MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) 2017-03-30 WO claimed
CN-103319890-B Polyimide-fiber-fabrpolyimide-resin-basecomposite polyimide-resin-basecomposite composite material and preparation method thereof BEIJING UNIVERSITY OF CHEMICAL TECHNOLOGY (CN) 2015-10-14 CN claimed
US-20150218192-A1 Polysilylated Organosilane Compounds CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2015-08-06 US claimed
CN-101314593-B Method for synthesis of benzimidazoline derivant UNIV SOOCHOW 2012-02-29 CN claimed
US-7834034-B2 Benzothiophene derivatives MERCK SHARP & DOHME CORP. (US) 2010-11-16 US claimed
US-20090012075-A1 Fluorinated Arylamide Derivatives MERCK SHARP & DOHME CORP. 2009-01-08 US claimed
CN-101314593-A Method for synthesis of benzimidazoline derivant UNIV SOOCHOW (CN) 2008-12-03 CN claimed
EP-1976511-A2 FLUORINATED ARYLAMIDE DERIVATIVES Merck & Co., Inc. (US) 2008-10-08 EP claimed
WO-2007087129-A2 FLUORINATED ARYLAMIDE DERIVATIVES MERCK & CO., INC. (US) 2007-08-02 WO claimed
US-20050070684-A1 Polyimide sulfones, method and articles made therefrom GENERAL ELECTRIC COMPANY 2005-03-31 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150218192-A1 Polysilylated Organosilane Compounds ALG8, UGT1A9, SI TDP1 2224/4885MEN1 775/4885KMT2A 516/4885
US-20090012075-A1 Fluorinated Arylamide Derivatives HDAC5, AADAC, HDAC6 TDP1 1564/4885MEN1 2902/4885KMT2A 27/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.