Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 8/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2669895 | 0.91 | ESR1 (0.42) | TP53MEN1KMT2AHIF1APOLB | |
| SCHEMBL2669960 | 0.88 | GCG (0.40) | TP53MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL9070790 | 0.87 | NAMPT (0.34) | TP53MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL2669769 | 0.86 | NAMPT (0.36) | TP53MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL2669989 | 0.85 | NAMPT (0.35) | TP53MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL2669958 | 0.84 | CASP3 (0.39) | MEN1KMT2AALDH1A1 | |
| SCHEMBL13069831 | 0.83 | NPC1 (0.33) | TP53MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2669955 | 0.82 | ESR1 (0.39) | — | |
| SCHEMBL9070778 | 0.82 | PTGS2 (0.42) | MEN1KMT2A | |
| SCHEMBL2669956 | 0.81 | MAOB (0.35) | TP53MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110520-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-09-11 | — | — | WO | disclosed |