Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | POLQ | O75417 | 3/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26699671 | 0.77 | LOXL2 (0.36) | IDO1 | |
| SCHEMBL30184485 | 0.77 | FFAR4 (0.40) | GLAPOLBGAATSHR | |
| SCHEMBL25033109 | 0.77 | FFAR4 (0.40) | GLAPOLBGAATSHR | |
| SCHEMBL545969 | 0.74 | GAA (0.57) | IDO1NR1H2GLAPOLBGAA | |
| SCHEMBL109671 | 0.74 | IDO1 (0.65) | IDO1SLC6A2SLC6A4HDAC3HDAC1 | |
| SCHEMBL25327887 | 0.74 | MAPT (0.43) | PDE3BPDE3A | |
| SCHEMBL25935807 | 0.73 | DDR1 (0.46) | SLC6A2SLC6A4EPHX2SLC6A3 | |
| SCHEMBL14224743 | 0.73 | SMN1; SMN2 (0.42) | IDO1NR1H2SLC6A2SLC6A4HTR2A | |
| SCHEMBL964552 | 0.71 | DAO (0.46) | IDO1TSHRPOLQ | |
| SCHEMBL31532451 | 0.70 | SLC6A4 (0.34) | SLC6A2SLC6A4HDAC6SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023226950-A1 | PEPTIDOMIMETIC STAT PROTEIN DEGRADER, COMPOSITION AND USE THEREOF | 杭州和正医药有限公司 | 2023-11-30 | — | — | WO | disclosed |
| CN-117126231-A | Peptoid STAT protein degradation agent, composition and application thereof | 杭州和正医药有限公司 | 2023-11-28 | — | — | CN | disclosed |