Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | AGXT | P21549 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28981163 | 0.80 | LOXL2 (0.35) | LOXL2IDO1AGXT | |
| SCHEMBL26699658 | 0.77 | IDO1 (0.39) | IDO1 | |
| SCHEMBL1491735 | 0.75 | ALDH1A1 (0.46) | — | |
| SCHEMBL12810877 | 0.72 | HDAC1 (0.44) | — | |
| SCHEMBL24981716 | 0.71 | ESR1 (0.37) | — | |
| SCHEMBL24899668 | 0.71 | HPGD (0.32) | — | |
| SCHEMBL29217886 | 0.71 | RAPGEF4 (0.36) | IDO1 | |
| SCHEMBL25388723 | 0.71 | KDM1A (0.35) | IDO1 | |
| SCHEMBL25146251 | 0.71 | SLC6A4 (0.43) | — | |
| SCHEMBL3161137 | 0.70 | TAAR1 (0.47) | LOXL2IDO1AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023226950-A1 | PEPTIDOMIMETIC STAT PROTEIN DEGRADER, COMPOSITION AND USE THEREOF | 杭州和正医药有限公司 | 2023-11-30 | — | — | WO | disclosed |
| CN-117126231-A | Peptoid STAT protein degradation agent, composition and application thereof | 杭州和正医药有限公司 | 2023-11-28 | — | — | CN | disclosed |